Not nobara related but I found a Linux Mint thread about using xinput to adjust config to have left handed mode enabled for 1 mouse but not another. Maybe that will help. If they’re wireless mice with dongles, maybe they’re struggling in that one mouse is connecting to both receivers? If they offer both bt and wifi pairing you might be able to get around it by manipulating that, or if they can be plugged in that might help.
Not nobara related but I found a Linux Mint thread about using xinput to adjust config to have left handed mode enabled for 1 mouse but not another. Maybe that will help. If they’re wireless mice with dongles, maybe they’re struggling in that one mouse is connecting to both receivers? If they offer both bt and wifi pairing you might be able to get around it by manipulating that, or if they can be plugged in that might help.