Global health agencies announced Wednesday that generic versions of a groundbreaking injectable drug to prevent HIV will be made available from 2027 at around $40 a year in more than 100 low and middle-income…
vaccine is a scientific term, meaning a weaker (or, rather, as weak as scientifically possible) version of the same virus / bacteria, so that immune system could learn to fight it without dying in the process.
This is not a vaccine, as has an active substance, that chemically interacts either with our body, HIV’s shell, or both
MRNA vaccine works differently if I remember well. Basically instead of injecting the weaker virus itself, they trick the body to produces non-active parts of that pathogens in order to train the body.
The core principle of vaccination is training the immune system with a substance so that a disease can be defeated later on.
Nothing says that a vaccine needs to be an injection. There are injection vaccines that need multiple doses before the immune system reaches a certain level.
So why would a pill that trains your immune system not be a vaccine?
A vaccine is administered to teach the immune system how to beat something. These drugs prevent certain processes in the virus replication cycle and have to be taken continuously for life to be effective.
It’s not a vaccine. It does not trigger an immune response.
Science says vaccines cannot be pills, they either need to be intramuscular or inhaled aerosol. This is because they are proteins, which get digested through the stomach and gut.
Some vaccine are oral based (but as a liquid, not as pill). We don’t use them in the West as we have robust viccine that are injection based. But those vaccine requires a way more robust supply chain than many third world countries has, so oral vaccine, while not as effective as injection based vaccine, are used there.
Problem with oral vaccine is that most pathogens are killed by the digestive system so the only one that could be made as a pill would be those who already are acclimated to such a harsh environment (so gut microbiology).
There are very few digestive disease that would allow for such vaccine vector to be developed, the only one that could these last few decade would be Ebola. But for such a deadly disease (90% mortality if I remember well), the medical community would prioritize the most effective way, which would be injection.
“Preventative drug”? Is this what we’re calling vaccines now?
HIV infects the immune cells, which is why attempts at vaccines failed.
Yeah HIV doesn’t use traditional warfare: it bombs hospitals. 😔
That’s standard warfare to some these days.
vaccine is a scientific term, meaning a weaker (or, rather, as weak as scientifically possible) version of the same virus / bacteria, so that immune system could learn to fight it without dying in the process.
This is not a vaccine, as has an active substance, that chemically interacts either with our body, HIV’s shell, or both
There are more ways, weak virus, dead virus, modified virus, payload swap virus and an mRNA blast.
Would love to see this HIV vac get more development and become permanent and a part of infant vaccine routine until it just fucking dies.
of course there are. I was axcited to hear about Vectors when they were developed. It’s nice to see scientists come up with something new
MRNA vaccine works differently if I remember well. Basically instead of injecting the weaker virus itself, they trick the body to produces non-active parts of that pathogens in order to train the body.
wow, cool, good to know something like that exists. What are we vaccinating against with MRNA?
Covid. Like 80% of the vaccine where mRNA based.
oh, cool
There are No vaccines for HIV. This is a drug that if taken continually will prevent the virus from taking hold.
It is an interesting what makes the distinction.
The core principle of vaccination is training the immune system with a substance so that a disease can be defeated later on.
Nothing says that a vaccine needs to be an injection. There are injection vaccines that need multiple doses before the immune system reaches a certain level.
So why would a pill that trains your immune system not be a vaccine?
A vaccine is administered to teach the immune system how to beat something. These drugs prevent certain processes in the virus replication cycle and have to be taken continuously for life to be effective.
It’s not a vaccine. It does not trigger an immune response. Science says vaccines cannot be pills, they either need to be intramuscular or inhaled aerosol. This is because they are proteins, which get digested through the stomach and gut.
Some vaccine are oral based (but as a liquid, not as pill). We don’t use them in the West as we have robust viccine that are injection based. But those vaccine requires a way more robust supply chain than many third world countries has, so oral vaccine, while not as effective as injection based vaccine, are used there.
Problem with oral vaccine is that most pathogens are killed by the digestive system so the only one that could be made as a pill would be those who already are acclimated to such a harsh environment (so gut microbiology).
There are very few digestive disease that would allow for such vaccine vector to be developed, the only one that could these last few decade would be Ebola. But for such a deadly disease (90% mortality if I remember well), the medical community would prioritize the most effective way, which would be injection.
There is also an oral polio vaccine that was developed.
Exactly, as the polio virus is resistant to digestive acids, and is transmited oraly, initially developing in the digestive system.
I guess a pill could be a vaccine, but this drug is neither a vaccine nor a pill, so I have no clue why youre bringing this up.